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Cellosaurus BC3H1 (CVCL_0163)

[Text version]
Cell line name BC3H1
Synonyms BC3 H1; BC3H-1; BC-3H-1; BC-3-H-I
Accession CVCL_0163
Resource Identification Initiative To cite this cell line use: BC3H1 (RRID:CVCL_0163)
Comments Characteristics: Closely resemble cells in an arrested state of skeletal muscle differentiation (PubMed=2715180).
Characteristics: The scorpion toxin Acra3 exerts a very strong cytotoxic effect this cell line (PubMed=24055552).
Doubling time: ~70 hours (DSMZ=ACC-171).
Transformant: ChEBI; CHEBI:23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Disease Mouse neoplasms (NCIt: C23988)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H.
Hierarchy Children:
CVCL_A5LH (BC3H1#1)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/b/cell-lines-detail-222.html
Publications

PubMed=4363958; DOI=10.1083/jcb.61.2.398
Schubert D., Harris A.J., Devine C.E., Heinemann S.F.
Characterization of a unique muscle cell line.
J. Cell Biol. 61:398-413(1974)

PubMed=2715180; DOI=10.1083/jcb.108.5.1799
Taubman M.B., Smith C.W.J., Izumo S., Grant J.W., Endo T., Andreadis A., Nadal-Ginard B.
The expression of sarcomeric muscle-specific contractile protein genes in BC3H1 cells: BC3H1 cells resemble skeletal myoblasts that are defective for commitment to terminal differentiation.
J. Cell Biol. 108:1799-1806(1989)

PubMed=10852349; DOI=10.1290/1071-2690(2000)036<0241:IOASFB>2.0.CO;2
Steenstrup T., Hannon K.
Isolation of a spontaneously fusing BC3H1 muscle cell line: fusion alters the response to serum stimulation.
In Vitro Cell. Dev. Biol. Anim. 36:241-248(2000)

PubMed=24055552; DOI=10.1016/j.toxicon.2013.09.009
Caliskan F., Ergene E., Sogut I., Hatipoglu I., Basalp A., Sivas H., Kanbak G.
Biological assays on the effects of Acra3 peptide from Turkish scorpion Androctonus crassicauda venom on a mouse brain tumor cell line (BC3H1) and production of specific monoclonal antibodies.
Toxicon 76:350-361(2013)

Cross-references
Cell line collections (Providers) ATCC; CRL-1443
DSMZ; ACC-171
ECACC; 86093001
IZSLER; BS TCL 145
KCLB; 21443
Cell line databases/resources CLO; CLO_0001894
MCCL; MCC:0000055
CLDB; cl398
CLDB; cl399
CLDB; cl5161
CCRID; 1101MOU-PUMC000096
DSMZCellDive; ACC-171
Anatomy/cell type resources BTO; BTO:0000115
Encyclopedic resources Wikidata; Q54795220
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19