Cellosaurus cell line M059K (CVCL_0401)

• Mutation; HGNC; 9588; PTEN; Simple; p.Pro204fs*17 (c.610delC); Zygosity=Homozygous (DepMap).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Glu286lys (c.856G>A); Zygosity=Homozygous (PubMed=11023613; DepMap).
  

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Radiation-induced DNA damage and repair in cells of a radiosensitive human malignant glioma cell line.
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PubMed=11023613; DOI=10.1667/0033-7587(2000)154[0473:HTFTMG]2.0.CO;2
Anderson C.W., Allalunis-Turner M.J.
Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8.
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PubMed=12105990; DOI=10.1667/0033-7587(2002)158[0195:DOAGMI]2.0.CO;2
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PubMed=18077418; DOI=10.1073/pnas.0707579104
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PubMed=21406405; DOI=10.1158/0008-5472.CAN-10-3112
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
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A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
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