Cellosaurus cell line DMS 153 (CVCL_1175)

• Mutation; HGNC; 11998; TP53; Simple; p.Thr155Pro (c.463A>C); Zygosity=Homozygous (PubMed=14660794; DepMap).
  

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Isolation and growth characteristics of continuous cell lines from small-cell carcinoma of the lung.
Cancer 45:906-918(1980)

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Vindelov L.L., Hansen H.H., Spang-Thomsen M.
Growth characteristics and heterogeneity of small cell carcinoma of the lung.
Recent Results Cancer Res. 97:47-54(1985)

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In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor.
Br. J. Cancer 78:631-640(1998)

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Hansen L.T., Lundin C., Spang-Thomsen M., Petersen L.N., Helleday T.
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int. J. Cancer 105:472-479(2003)

PubMed=14660794; DOI=10.1073/pnas.2536558100
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Inhibition of mutant p53 expression and growth of DMS-153 small cell lung carcinoma by antagonists of growth hormone-releasing hormone and bombesin.
Proc. Natl. Acad. Sci. U.S.A. 100:15836-15841(2003)

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Signatures of mutation and selection in the cancer genome.
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PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
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PubMed=22460905; DOI=10.1038/nature11003
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112
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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
Cancer Discov. 2:798-811(2012)

PubMed=25877200; DOI=10.1038/nature14397
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A resource for cell line authentication, annotation and quality control.
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PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
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PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)