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Cellosaurus EFM-192B (CVCL_1813)

[Text version]
Cell line name EFM-192B
Synonyms EFM192B
Accession CVCL_1813
Resource Identification Initiative To cite this cell line use: EFM-192B (RRID:CVCL_1813)
Comments Part of: GrayJW breast cancer cell line panel.
Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~4-5 days (DSMZ=ACC-308); 68.47 hours (GrayJW panel).
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
HLA typing Source: PubMed=25960936
Class I
HLA-AA*01:01,24:02
HLA-BB*07:02,39:01
HLA-CC*07:02,12:03
Class II
HLA-DQDQB1*06:02,02:02
HLA-DRDRB1*15:01,09:10

Source: PubMed=26589293
Class I
HLA-AA*01:01,24:02
HLA-BB*07:02,39:01
HLA-CC*07:02,12:03
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1812 ! EFM-192A
CVCL_1814 ! EFM-192C
Sex of cell Female
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO12,13
D2S133817,25
D3S135814,16
D5S81812,13
D7S8208,11
D8S117910
D13S3179,14
D16S5398,13
D18S5117
D19S43314
D21S1132.2
FGA20,22
Penta D9
Penta E14,16
TH017
TPOX8,10
vWA16

Run an STR similarity search on this cell line
Web pages https://www.synapse.org/#!Synapse:syn2346643/wiki/62255
https://tcpaportal.org/mclp/
Publications

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110
Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C.B., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y.-L., Mills G.B., Cho R.J., Collisson E.A., van 't Veer L.J., Spellman P.T., Gray J.W.
Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-308
Cell line databases/resources CLO; CLO_0002890
Cell_Model_Passport; SIDM01054
DSMZCellDive; ACC-308
LINCS_HMS; 51115
LINCS_LDP; LCL-1312
Chemistry resources PharmacoDB; EFM192B_323_2019
Encyclopedic resources Wikidata; Q54832053
Experimental variables resources EFO; EFO_0006569
Gene expression databases ArrayExpress; E-MTAB-2706
GEO; GSM1172951
GEO; GSM1172859
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number26