Home  |  Contact

Cellosaurus SK-MEL-495 (CVCL_1T99)

[Text version]
Cell line name SK-MEL-495
Synonyms SK-Mel-495
Accession CVCL_1T99
Resource Identification Initiative To cite this cell line use: SK-MEL-495 (RRID:CVCL_1T99)
Comments From: Memorial Sloan Kettering Cancer Center; New York; USA.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=24576830).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625
Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L., Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A., Chapman P.B., Yaeger R., Taylor B.S., Schultz N., Berger M.F., Rosen N., Solit D.B.
Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.
Cancer Res. 74:2340-2350(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_1T99
Encyclopedic resources Wikidata; Q54954246
Entry history
Entry creation08-Jul-2015
Last entry update05-Oct-2023
Version number9