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Cellosaurus H103 (CVCL_2457)

[Text version]
Cell line name H103
Accession CVCL_2457
Resource Identification Initiative To cite this cell line use: H103 (RRID:CVCL_2457)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Karyotypic information: Has lost chromosome Y.
Omics: Deep exome analysis.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly244Cys (c.730G>T); ClinVar=VCV000376599; Zygosity=Homozygous (PubMed=7633286; DepMap).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 32Y
Category Cancer cell line
STR profile Source(s): DepMap; ECACC

Markers:
AmelogeninX
CSF1PO9,10
D3S135817
D5S81810,11
D7S82010
D8S117912,13
D13S31712,13
D16S53911,12
D18S5115
D21S1130
FGA21,23
Penta D9,11
Penta E20
TH018,9
TPOX8,9
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=1692339; DOI=10.1002/path.1711600313
Prime S.S., Nixon S.V.R., Crane I.J., Stone A., Matthews J.B., Maitland N.J., Remnant L., Powell S.K., Game S.M., Scully C.
The behaviour of human oral squamous cell carcinoma in cell culture.
J. Pathol. 160:259-269(1990)

PubMed=1744799; DOI=10.1002/path.1711650208
Mutlu S., Matthews J.B., Midda M., Scully C., Prime S.S.
MHC antigen expression in human oral squamous carcinoma cell lines.
J. Pathol. 165:129-136(1991)

PubMed=7633286; DOI=10.1016/0964-1955(94)00030-8
Yeudall W.A., Paterson I.C., Patel V., Prime S.S.
Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53.
Eur. J. Cancer B Oral Oncol. 31:136-143(1995)

Cross-references
Cell line collections (Providers) CancerTools; 153419
ECACC; 06092001
Ximbio; 153419
Cell line databases/resources Cell_Model_Passport; SIDM01568
DepMap; ACH-001346
Chemistry resources ChEMBL-Cells; CHEMBL4483157
ChEMBL-Targets; CHEMBL4483241
PubChem_Cell_line; CVCL_2457
Encyclopedic resources Wikidata; Q54871913
Polymorphism and mutation databases Cosmic; 716673
Cosmic; 916367
Cosmic; 928234
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19