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Cellosaurus NO36 (CVCL_2658)

[Text version]
Cell line name NO36
Accession CVCL_2658
Resource Identification Initiative To cite this cell line use: NO36 (RRID:CVCL_2658)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Transformant: ChEBI; CHEBI:46666; Crocidolite asbestos.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 950; BAP1; Simple; p.Phe118Leufs*69 (c.354delC); Zygosity=Heterozygous (PubMed=21642991; DepMap).
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 36-62Y
Category Cancer cell line
STR profile Source(s): CBA

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133825
D3S135815,16
D5S81812,13
D7S82011
D8S117912
D13S3178
D16S53911,13
D18S5121,22
D19S43315,16
D21S1128,29
FGA22
TH016,7
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=1703129; DOI=10.1002/ijc.2910470219
Manning L.S., Whitaker D., Murch A.R., Garlepp M.J., Davis M.R., Musk A.W., Robinson B.W.S.
Establishment and characterization of five human malignant mesothelioma cell lines derived from pleural effusions.
Int. J. Cancer 47:285-290(1991)

PubMed=21642991; DOI=10.1038/ng.855
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

PubMed=25902174; DOI=10.1097/JTO.0000000000000493
Miyanaga A., Masuda M., Tsuta K., Kawasaki K., Nakamura Y., Sakuma T., Asamura H., Gemma A., Yamada T.
Hippo pathway gene mutations in malignant mesothelioma: revealed by RNA and targeted exon sequencing.
J. Thorac. Oncol. 10:844-851(2015)

Cross-references
Cell line collections (Providers) CBA; CBA-0142
ECACC; 10092312
Cell line databases/resources cancercelllines; CVCL_2658
DepMap; ACH-001977
Biological sample resources BioSample; SAMN07624411
Encyclopedic resources Wikidata; Q54930861
Gene expression databases GEO; GSM796439
Polymorphism and mutation databases Cosmic; 1522764
Cosmic; 1963331
Progenetix; CVCL_2658
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20