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Cellosaurus MY-M12 (CVCL_3035)

[Text version]
Cell line name MY-M12
Synonyms MY clone M12; MYM12
Accession CVCL_3035
Resource Identification Initiative To cite this cell line use: MY-M12 (RRID:CVCL_3035)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: DNA methylation analysis.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mononuclear cell; CL=CL_0000842.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.94
Native American0.38
East Asian, North81.47
East Asian, South16.04
South Asian1.17
European, North0
European, South0
Disease Acute biphenotypic leukemia (NCIt: C4673)
Mixed phenotype acute leukemia (ORDO: Orphanet_530995)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3034 (MY)
Sex of cell Female
Age at sampling 52Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,13
D7S82010,13
D13S3178
D16S5399
TH019
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=9790503; DOI=10.1002/(SICI)1098-2264(199811)23:3<227::AID-GCC4>3.0.CO;2-3
Inokuchi K., Shinohara T., Futaki M., Hanawa H., Tanosaki S., Yamaguchi H., Nomura T., Dan K.
Establishment of a cell line with variant BCR/ABL breakpoint expressing P180BCR/ABL from late-appearing Philadelphia-positive acute biphenotypic leukemia.
Genes Chromosomes Cancer 23:227-238(1998)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X.-M., Egan R.K., Liu Q.-S., Mironenko T., Mitropoulos X., Richardson L., Wang J.-H., Zhang T.-H., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB0158.1
JCRB; NIHS0246.1 - Discontinued
Cell line databases/resources CLO; CLO_0037185
cancercelllines; CVCL_3035
Cell_Model_Passport; SIDM01217
Cosmic-CLP; 1330960
DepMap; ACH-002276
LINCS_LDP; LCL-1002
Chemistry resources GDSC; 1330960
PharmacoDB; MYM12_974_2019
Encyclopedic resources Wikidata; Q54907142
Gene expression databases GEO; GSM1670138
Polymorphism and mutation databases Cosmic; 2131569
Proteomic databases PRIDE; PXD030304
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number29