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Cellosaurus NCC-StC-K140 (CVCL_3055)

[Text version]
Cell line name NCC-StC-K140
Synonyms NCCStCK140; NCCSTCK140; K140
Accession CVCL_3055
Resource Identification Initiative To cite this cell line use: NCC-StC-K140 (RRID:CVCL_3055)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Japanese.
Doubling time: ~44 hours (Note=Lot 03222018) (JCRB=JCRB1228).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Stomach; UBERON=UBERON_0000945.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (DepMap).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.19
Native American0
East Asian, North80.7
East Asian, South13.81
South Asian0
European, North0
European, South4.29
Disease Gastric carcinoma (NCIt: C4911)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): JCRB; RCB

Markers:
AmelogeninX
CSF1PO10
D5S8189
D7S82011,12 (JCRB)
12 (RCB)
D13S31712
D16S53912
TH017,9
TPOX8,11
vWA14

Run an STR similarity search on this cell line
Publications

PubMed=8263010; DOI=10.1007/BF01202193
Inomata M., Kaneko A., Saijo N., Tokura S.
Culture of retinoblastoma cells from clinical specimens: growth-promoting effect of 2-mercaptoethanol.
J. Cancer Res. Clin. Oncol. 120:149-155(1994)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections (Providers) JCRB; JCRB1228
RCB; RCB2224
Cell line databases/resources CLO; CLO_0050803
cancercelllines; CVCL_3055
Cell_Model_Passport; SIDM01682
DepMap; ACH-000110
Biological sample resources BioSample; SAMN03472022
BioSample; SAMN03472448
BioSample; SAMN10988058
Chemistry resources PharmacoDB; NCCStCK140_996_2019
Encyclopedic resources Wikidata; Q54907635
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM888427
Polymorphism and mutation databases IARC_TP53; 28306
LiGeA; CCLE_272
Progenetix; CVCL_3055
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20