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Cellosaurus TASK1 (CVCL_3177)

[Text version]
Cell line name TASK1
Accession CVCL_3177
Resource Identification Initiative To cite this cell line use: TASK1 (RRID:CVCL_3177)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 38 hours (PubMed=9661044).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Chest wall; UBERON=UBERON_0016435.
Sequence variations
  • Gene fusion; HGNC; 3508; EWSR1 + HGNC; 3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1 (PubMed=9661044).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.94
Native American0.97
East Asian, North86.4
East Asian, South7.58
South Asian0.24
European, North0
European, South2.87
Disease Askin tumor (NCIt: C7542)
Peripheral primitive neuroectodermal tumor (ORDO: Orphanet_370348)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 21Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DepMap; JCRB

Markers:
AmelogeninX
CSF1PO10
D3S135818
D5S81813
D7S82012
D8S117910
D13S3178
D16S53912
D18S5114
D21S1130,31
FGA23
Penta D9,11
Penta E5,11
TH019
TPOX11
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=9661044; DOI=10.1007/s11626-998-0074-1
Horiguchi H., Matsui M., Ohtsubo R., Ogata T., Kaneko M., Fujiwara M., Kamma H.
Establishment and characterization of a typical primitive neuroectodermal tumor cell line.
In Vitro Cell. Dev. Biol. Anim. 34:439-442(1998)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections (Providers) JCRB; JCRB0139
JCRB; NIHS0202 - Discontinued
Cell line databases/resources CLO; CLO_0037092
cancercelllines; CVCL_3177
Cell_Model_Passport; SIDM00026
Cosmic-CLP; 1299067
DepMap; ACH-001670
LINCS_LDP; LCL-1114
Biological sample resources BioSample; SAMN03470806
Chemistry resources GDSC; 1299067
PharmacoDB; TASK1_1565_2019
Encyclopedic resources Wikidata; Q54971734
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827197
GEO; GSM1670524
Polymorphism and mutation databases Progenetix; CVCL_3177
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number29