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Cellosaurus CFSC-2G (CVCL_4U34)

[Text version]
Cell line name CFSC-2G
Accession CVCL_4U34
Resource Identification Initiative To cite this cell line use: CFSC-2G (RRID:CVCL_4U34)
Comments Karyotypic information: Hyperdiploid karyotype (PubMed=36139474).
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatic stellate cell; CL=CL_0000632.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar.
Hierarchy Parent: CVCL_M104 (CFSC)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=8394478
Greenwel P., Rubin J., Schwartz M., Hertzberg E.L., Rojkind M.
Liver fat-storing cell clones obtained from a CCl4-cirrhotic rat are heterogeneous with regard to proliferation, expression of extracellular matrix components, interleukin-6, and connexin 43.
Lab. Invest. 69:210-216(1993)

PubMed=7635427; DOI=10.1002/hep.1840220230
Inagaki Y., Truter S., Greenwel P., Rojkind M., Unoura M., Kobayashi K., Ramirez F.
Regulation of the alpha 2(I) collagen gene transcription in fat-storing cells derived from a cirrhotic liver.
Hepatology 22:573-579(1995)

PubMed=17760834; DOI=10.1111/j.1582-4934.2007.00060.x
Herrmann J., Gressner A.M., Weiskirchen R.
Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?
J. Cell. Mol. Med. 11:704-722(2007)

PubMed=20594261; DOI=10.1111/j.1440-1746.2009.06175.x
Gonzalez-Puertos V.Y., Hernandez-Perez E., Nuno-Lambarri N., Ventura-Gallegos J.L., Lopez-Diazguerrero N.E., Robles-Diaz G., Gutierrez-Ruiz M.C., Konigsberg M.
Bcl-2 overexpression in hepatic stellate cell line CFSC-2G, induces a pro-fibrotic state.
J. Gastroenterol. Hepatol. 25:1306-1314(2010)

PubMed=36139474; DOI=10.3390/cells11182900
Nanda I., Schroder S.K., Steinlein C., Haaf T., Buhl E.M., Grimm D.G., Weiskirchen R.
Rat hepatic stellate cell line CFSC-2G: genetic markers and short tandem repeat profile useful for cell line authentication.
Cells 11:2900.1-2900.19(2022)

Cross-references
Encyclopedic resources Wikidata; Q54811454
Entry history
Entry creation22-Sep-2015
Last entry update29-Jun-2023
Version number6