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Cellosaurus IOSE-29 (CVCL_5535)

Cell line name IOSE-29
Synonyms IOSE 29; IOSE29; NFHIOSE-29; IOSE-Mar; IOSE-MAR
Accession CVCL_5535
Resource Identification Initiative To cite this cell line use: IOSE-29 (RRID:CVCL_5535)
Comments From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada.
Doubling time: 33.7 hours (PubMed=10329039).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5536 (IOSE-29EC)CVCL_2G67 (T29)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1326894; DOI=10.1016/S0002-9378(11)91579-8
Maines-Bandiera S.L., Kruk P.A., Auersperg N.
Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix.
Am. J. Obstet. Gynecol. 167:729-735(1992)

PubMed=7967506
Auersperg N., Maines-Bandiera S.L., Dyck H.G., Kruk P.A.
Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes.
Lab. Invest. 71:510-518(1994)

PubMed=10329039; DOI=10.1006/gyno.1999.5348
Kruk P.A., Godwin A.K., Hamilton T.C., Auersperg N.
Telomeric instability and reduced proliferative potential in ovarian surface epithelial cells from women with a family history of ovarian cancer.
Gynecol. Oncol. 73:229-236(1999)

PubMed=10339573; DOI=10.1073/pnas.96.11.6249
Auersperg N., Pan J., Grove B.D., Peterson T., Fisher J., Maines-Bandiera S.L., Somasiri A., Roskelley C.D.
E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium.
Proc. Natl. Acad. Sci. U.S.A. 96:6249-6254(1999)

PubMed=19926575; DOI=10.1309/AJCPTK87EMMIKPFS
DeRycke M.S., Andersen J.D., Harrington K.M., Pambuccian S.E., Kalloger S.E., Boylan K.L.M., Argenta P.A., Skubitz A.P.N.
S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival.
Am. J. Clin. Pathol. 132:846-856(2009)

PubMed=20204287; DOI=10.3892/or_00000728
Langland G.T., Yannone S.M., Langland R.A., Nakao A., Guan Y.-H., Long S.B.T., Vonguyen L., Chen D.J., Gray J.W., Chen F.-Q.
Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities.
Oncol. Rep. 23:1021-1026(2010)

PubMed=23415752; DOI=10.1016/j.molonc.2012.12.007
Stordal B., Timms K., Farrelly A., Gallagher D., Busschots S., Renaud M., Thery J., Williams D., Potter J., Tran T., Korpanty G., Cremona M., Carey M.S., Li J., Li Y., Aslan O., O'Leary J.J., Mills G.B., Hennessy B.T.
BRCA1/2 mutation analysis in 41 ovarian cell lines reveals only one functionally deleterious BRCA1 mutation.
Mol. Oncol. 7:567-579(2013)

Cross-references
Anatomy/cell type resources BTO; BTO:0004132
Encyclopedic resources Wikidata; Q54897886
Polymorphism and mutation databases IARC_TP53; 28486
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number19