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Cellosaurus H-MESO-1A (CVCL_5760)

[Text version]
Cell line name H-MESO-1A
Synonyms H-Meso-1A; H-Meso 1A; H-Meso1A; HMeso01A; HMESO1A; HMeso1A
Accession CVCL_5760
Resource Identification Initiative To cite this cell line use: H-MESO-1A (RRID:CVCL_5760)
Comments Transformant: ChEBI; CHEBI:46661; Asbestos.
Omics: SNP array analysis.
Misspelling: H-Messo-1A; Note=Occasionally.
Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
Sequence variations
  • Gene deletion; HGNC; 950; BAP1; Zygosity=Heterozygous (PubMed=21642991).
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=21642991).
  • Mutation; HGNC; 950; BAP1; Simple; p.Glu685Val (c.2054A>T); Zygosity=Heterozygous (PubMed=21642991).
Disease Pleural biphasic mesothelioma (NCIt: C45665)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5759 (H-MESO-1)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): CLS

Markers:
AmelogeninX,Y
CSF1PO11,12
D3S135814
D5S81810,12
D7S82012
D8S117910
D13S31711
D16S53912
D18S5114,20
D21S1130,33.2
FGA23
Penta D11,13
Penta E7,11
TH016,9.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=21642991; DOI=10.1038/ng.855
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

Cross-references
Cell line collections (Providers) CLS; 300187
Cell line databases/resources cancercelllines; CVCL_5760
Biological sample resources BioSamples; SAMEA100945
Encyclopedic resources Wikidata; Q54871891
Gene expression databases GEO; GSM726269
Polymorphism and mutation databases Cosmic; 1522768
Cosmic; 1541205
Progenetix; CVCL_5760
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23