Home  |  Contact

Cellosaurus K177 (CVCL_5I63)

[Text version]
Cell line name K177
Synonyms K-177
Accession CVCL_5I63
Resource Identification Initiative To cite this cell line use: K177 (RRID:CVCL_5I63)
Comments Transfected with: HGNC; 1958; CHRNA4.
Transfected with: HGNC; 1962; CHRNB2.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=8558445
Gopalakrishnan M., Monteggia L.M., Anderson D.J., Molinari E.J., Piattoni-Kaplan M., Donnelly-Roberts D., Arneric S.P., Sullivan J.P.
Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor.
J. Pharmacol. Exp. Ther. 276:289-297(1996)

PubMed=8987816
Buisson B., Gopalakrishnan M., Arneric S.P., Sullivan J.P., Bertrand D.
Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: a patch-clamp study.
J. Neurosci. 16:7880-7891(1996)

PubMed=11245666; DOI=10.1523/JNEUROSCI.21-06-01819.2001
Buisson B., Bertrand D.
Chronic exposure to nicotine upregulates the human (alpha)4((beta)2 nicotinic acetylcholine receptor function.
J. Neurosci. 21:1819-1829(2001)

Cross-references
Chemistry resources ChEMBL-Cells; CHEMBL3308619
ChEMBL-Targets; CHEMBL614687
PubChem_Cell_line; CVCL_5I63
Encyclopedic resources Wikidata; Q54899263
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number10