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Cellosaurus GAY2911 (CVCL_7956)

[Text version]
Cell line name GAY2911
Accession CVCL_7956
Resource Identification Initiative To cite this cell line use: GAY2911 (RRID:CVCL_7956)
Comments Omics: Secretome proteome analysis.
Omics: SNP array analysis.
Sequence variations
  • Mutation; HGNC; 950; BAP1; Simple; p.Arg57fs*15 (c.170delG); Zygosity=Heterozygous (PubMed=21642991).
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
Publications

PubMed=21642991; DOI=10.1038/ng.855
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

PubMed=28387650; DOI=10.21873/cgp.20023
Creaney J., Dick I.M., Leon J.S., Robinson B.W.S.
A proteomic analysis of the malignant mesothelioma secretome using iTRAQ.
Cancer Genomics Proteomics 14:103-117(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7956
Biological sample resources BioSamples; SAMEA100803
Encyclopedic resources Wikidata; Q54835445
Gene expression databases GEO; GSM726263
Polymorphism and mutation databases Cosmic; 1522762
Progenetix; CVCL_7956
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number15