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Cellosaurus TTC-516 (CVCL_8004)

Cell line name TTC-516
Synonyms TTC516; TC-516; TU-516; A995
Accession CVCL_8004
Resource Identification Initiative To cite this cell line use: TTC-516 (RRID:CVCL_8004)
Comments Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 12Y
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133819
D3S135814,15
D5S81810,13
D7S82010,11
D8S117913,14
D13S31711,12
D16S5399,11
D18S5115,16
D19S43314
D21S1127,31.2
FGA22,24
TH019
TPOX9
vWA17,19

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Publications

CLPUB00569
Dickman P.S., Tsokos M.G., Triche T.J.
Biology of rhabdomyosarcoma: cell culture, xenografts, and animal models.
(In) Rhabdomyosarcoma and related tumors in children and adolescents; Maurer H.M., Ruymann F.B., Pochedly C.E. (eds.); pp.49-88; CRC Press; Boca Raton (1991)

PubMed=7882340
Sorensen P.H.B., Shimada H., Liu X.F., Lim J.F., Thomas G., Triche T.J.
Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene.
Cancer Res. 55:1385-1392(1995)

PubMed=10602515; DOI=10.1038/sj.onc.1203168
DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
Oncogene 18:7559-7565(1999)

PubMed=19887553; DOI=10.1158/1535-7163.MCT-09-0365
Hu K.-J., Lee C., Qiu D.-X., Fotovati A., Davies A., Abu-Ali S., Wai D.H., Lawlor E.R., Triche T.J., Pallen C.J., Dunn S.E.
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas.
Mol. Cancer Ther. 8:3024-3035(2009)

PubMed=23882450; DOI=10.3389/fonc.2013.00183
Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G., Linardic C.M.
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

PubMed=23665679; DOI=10.1038/onc.2013.129
Sokolowski E., Turina C.B., Kikuchi K., Langenau D.M., Keller C.
Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.
Oncogene 33:1877-1889(2014)

Cross-references
Encyclopedic resources Wikidata; Q54973241
Polymorphism and mutation databases Cosmic; 802051
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number16