Home  |  Contact

Cellosaurus Detroit 98 (CVCL_8188)

[Text version]
Cell line name Detroit 98
Synonyms Detroit-98; Det-98; Det98; D98
Accession CVCL_8188
Resource Identification Initiative To cite this cell line use: Detroit 98 (RRID:CVCL_8188)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from the bone marrow of a non cancerous individual.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00005.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_8192 (Detroit 98S)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=13370509; DOI=10.3181/00379727-92-22595
Berman L., Stulberg C.S.
Eight culture strains (Detroit) of human epithelial-like cells.
Proc. Soc. Exp. Biol. Med. 92:730-735(1956)

PubMed=13460970
Berman L., Stulberg C.S., Ruddle F.H.
Human cell culture: morphology of the Detroit strains.
Cancer Res. 17:668-676(1957)

PubMed=14185313; DOI=10.1126/science.146.3641.241
Cell Culture Collection Committee
Animal cell strains. The Cell Culture Collection Committee has assembled and certified 23 strains of animal cells.
Science 146:241-243(1964)

PubMed=4864103
Gartler S.M.
Genetic markers as tracers in cell culture.
Natl. Cancer Inst. Monogr. 26:167-195(1967)

PubMed=5641128; DOI=10.1038/217750a0
Gartler S.M.
Apparent Hela cell contamination of human heteroploid cell lines.
Nature 217:750-751(1968)

DOI=10.1007/BF02618370
Stulberg C.S., Coriell L.L., Kniazeff A.J., Shannon J.E.
The animal cell culture collection.
In Vitro 5:1-16(1970)

DOI=10.1007/978-1-4757-1647-4_13
Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=1246601; DOI=10.1126/science.1246601
Nelson-Rees W.A., Flandermeyer R.R.
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=566722; DOI=10.1007/BF02616110
Lavappa K.S.
Survey of ATCC stocks of human cell lines for HeLa contamination.
In Vitro 14:469-475(1978)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections (Providers) ATCC; CCL-18 - Discontinued
Biological sample resources BioSample; SAMN03151686
Chemistry resources ChEMBL-Cells; CHEMBL3307294
ChEMBL-Targets; CHEMBL614059
PubChem_Cell_line; CVCL_8188
Encyclopedic resources Wikidata; Q54831006
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number26