Home  |  Contact

Cellosaurus 29b (CVCL_9000)

[Text version]
Cell line name 29b
Synonyms 29B; A29b; 29b-ALS
Accession CVCL_9000
Secondary accession CVCL_B521
Resource Identification Initiative To cite this cell line use: 29b (RRID:CVCL_9000)
Comments From: Harvard University; Boston; USA.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 11179; SOD1; Simple; p.Leu145Phe (c.435G>C) (L144F); ClinVar=VCV000586637; Zygosity=Unspecified (PubMed=21293464).
Disease Amyotrophic lateral sclerosis 1 (NCIt: C168749)
Amyotrophic lateral sclerosis (ORDO: Orphanet_803)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_8999 ! 29a
CVCL_B522 ! 29c
CVCL_9001 ! 29d
CVCL_9002 ! 29e
Sex of cell Female
Age at sampling 82Y
Category Induced pluripotent stem cell
Publications

PubMed=18669821; DOI=10.1126/science.1158799
Dimos J.T., Rodolfa K.T., Niakan K.K., Weisenthal L.M., Mitsumoto H., Chung W.K., Croft G.F., Saphier G., Leibel R.L., Goland R.S., Wichterle H., Henderson C.E., Eggan K.C.
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons.
Science 321:1218-1221(2008)

PubMed=21293464; DOI=10.1038/nbt.1783
Boulting G.L., Kiskinis E., Croft G.F., Amoroso M.W., Oakley D.H., Wainger B.J., Williams D.J., Kahler D.J., Yamaki M., Davidow L.S., Rodolfa C.T., Dimos J.T., Mikkilineni S., MacDermott A.B., Woolf C.J., Henderson C.E., Wichterle H., Eggan K.C.
A functionally characterized test set of human induced pluripotent stem cells.
Nat. Biotechnol. 29:279-286(2011)

Cross-references
Cell line databases/resources ISCR; 213
SKIP; SKIP004436
Encyclopedic resources Wikidata; Q54584271
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number18