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Cellosaurus UOK120 (CVCL_B099)

Cell line name UOK120
Synonyms UOK-120; UOK 120
Accession CVCL_B099
Resource Identification Initiative To cite this cell line use: UOK120 (RRID:CVCL_B099)
Comments Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Gene fusion; HGNC; 9343; PRCC + HGNC; 11752; TFE3; Name(s)=PRCC-TFE3 (PubMed=8872474).
Disease Papillary renal cell carcinoma (NCIt: C6975)
Papillary renal cell carcinoma (ORDO: Orphanet_319298)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
Publications

PubMed=1345811
Anglard P., Trahan E., Liu S., Latif F., Merino M.J., Lerman M.I., Zbar B., Linehan W.M.
Molecular and cellular characterization of human renal cell carcinoma cell lines.
Cancer Res. 52:348-356(1992)

PubMed=8319216
Reiter R.E., Anglard P., Liu S., Gnarra J.R., Linehan W.M.
Chromosome 17p deletions and p53 mutations in renal cell carcinoma.
Cancer Res. 53:3092-3097(1993)

PubMed=7587394; DOI=10.1159/000134127
Shipley J.M., Birdsall S., Clark J., Crew J., Gill S., Linehan W.M., Gnarra J.R., Fisher S., Craig I.W., Cooper C.S.
Mapping the X chromosome breakpoint in two papillary renal cell carcinoma cell lines with a t(X;1)(p11.2;q21.2) and the first report of a female case.
Cytogenet. Cell Genet. 71:280-284(1995)

PubMed=8872474; DOI=10.1093/hmg/5.9.1333
Sidhar S.K., Clark J., Gill S., Hamoudi R., Crew A.J., Gwilliam R., Ross M., Linehan W.M., Birdsall S., Shipley J.M., Cooper C.S.
The t(X;1)(p11.2;q21.2) translocation in papillary renal cell carcinoma fuses a novel gene PRCC to the TFE3 transcription factor gene.
Hum. Mol. Genet. 5:1333-1338(1996)

PubMed=9255309; DOI=10.1016/S0090-4295(97)00220-3
Walther M.M., Kleiner D.E., Lubensky I.A., Pozzatti R., Nyguen T., Gnarra J.R., Hurley K., Venzon D., Linehan W.M., Stetler-Stevenson W.G.
Progelatinase A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival.
Urology 50:295-301(1997)

PubMed=27993170; DOI=10.1186/s12943-016-0565-8
Brodaczewska K.K., Szczylik C., Fiedorowicz M., Porta C., Czarnecka A.M.
Choosing the right cell line for renal cell cancer research.
Mol. Cancer 15:83.1-83.15(2016)

Cross-references
Encyclopedic resources Wikidata; Q54991334
Polymorphism and mutation databases Cosmic; 1330966
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number14