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Cellosaurus HOK-16B (CVCL_B405)

Cell line name HOK-16B
Synonyms HOK16B; Human Oral Keratinocytes-16B
Accession CVCL_B405
Resource Identification Initiative To cite this cell line use: HOK-16B (RRID:CVCL_B405)
Comments Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Oral cavity; UBERON=UBERON_0000167.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B406 (HOK-16B-BaP)CVCL_6G60 (HOK-16B-MSEE)
Originate from same individual CVCL_B404 ! HOK-16A
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO10,11
D5S8189,10
D7S82012
D13S3179,12
D16S53912
TH018,9
TPOX8,11
vWA17,19

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Publications

PubMed=1654226; DOI=10.1093/carcin/12.9.1627
Park N.-H., Min B.-M., Li S.-L., Huang M.-Z., Cherick H.M., Doniger J.
Immortalization of normal human oral keratinocytes with type 16 human papillomavirus.
Carcinogenesis 12:1627-1631(1991)

PubMed=1330348; DOI=10.1093/carcin/13.11.1981
Li S.-L., Kim M.S., Cherrick H.M., Doniger J., Park N.-H.
Sequential combined tumorigenic effect of HPV-16 and chemical carcinogens.
Carcinogenesis 13:1981-1987(1992)

PubMed=10675494; DOI=10.3892/ijo.16.3.591
Itakura M., Mori S., Park N.-H., Bonavida B.
Both HPV and carcinogen contribute to the development of resistance to apoptosis during oral carcinogenesis.
Int. J. Oncol. 16:591-597(2000)

PubMed=12907203; DOI=10.1016/S1368-8375(03)00049-6
Swan E.A., Jasser S.A., Holsinger F.C., Doan D., Bucana C.D., Myers J.N.
Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer.
Oral Oncol. 39:648-655(2003)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

PubMed=32574978; DOI=10.1016/j.tranon.2020.100808
Nair T.S., Thomas T.B., Yang L., Kakaraparthi B.N., Morris A.C., Clark A.M., Campredon L.P., Brouwer A.F., Eisenberg M.C., Meza R., Carey T.E.
Characteristics of head and neck squamous cell carcinoma cell lines reflect human tumor biology independent of primary etiologies and HPV status.
Transl. Oncol. 13:100808.1-100808.9(2020)

Cross-references
Encyclopedic resources Wikidata; Q54890135
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number13