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Cellosaurus MEL-STR (CVCL_C854)

[Text version]
Cell line name MEL-STR
Accession CVCL_C854
Resource Identification Initiative To cite this cell line use: MEL-STR (RRID:CVCL_C854)
Comments Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
Transfected with: HGNC; 11730; TERT.
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Melanocyte of foreskin; CL=CL_2000045.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9U70 ! MEL-STM
CVCL_9U71 ! MEL-STV
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=16142232; DOI=10.1038/ng1634
Gupta P.B., Kuperwasser C., Brunet J.-P., Ramaswamy S., Kuo W.-L., Gray J.W., Naber S.P., Weinberg R.A.
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation.
Nat. Genet. 37:1047-1054(2005)

Cross-references
Encyclopedic resources Wikidata; Q54905139
Polymorphism and mutation databases Cosmic; 1458969
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number10