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Cellosaurus A2780/ACRP (CVCL_D157)

[Text version]
Cell line name A2780/ACRP
Synonyms ACRP
Accession CVCL_D157
Resource Identification Initiative To cite this cell line use: A2780/ACRP (RRID:CVCL_D157)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Unspecified (from parent cell line).
Disease Ovarian endometrioid adenocarcinoma (NCIt: C7979)
Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0134 (A2780)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): BCRJ

Markers:
AmelogeninX
CSF1PO10,11
D2S133821,22
D3S135814,16
D5S81811,12
D7S82010
D8S117915,17
D13S31712,13
D16S53911,13
D18S5116,18
D19S43312
D21S1128
FGA19,23
TH016
TPOX8,10
vWA15,16

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Publications

PubMed=12726863; DOI=10.1016/S1535-6108(03)00058-8
Sherman-Baust C.A., Weeraratna A.T., Rangel L.B.A., Pizer E.S., Cho K.R., Schwartz D.R., Shock T., Morin P.J.
Remodeling of the extracellular matrix through overexpression of collagen VI contributes to cisplatin resistance in ovarian cancer cells.
Cancer Cell 3:377-386(2003)

Cross-references
Cell line collections (Providers) BCRJ; 0036
Cell line databases/resources cancercelllines; CVCL_D157
Encyclopedic resources Wikidata; Q54606587
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number16