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Cellosaurus MYL-R (CVCL_D203)

[Text version]
Cell line name MYL-R
Accession CVCL_D203
Resource Identification Initiative To cite this cell line use: MYL-R (RRID:CVCL_D203)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:45783; Imatinib (Gleevec; STI571).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=17432977).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D202 (MYL)
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
Publications

PubMed=17432977; DOI=10.1111/j.1600-0609.2007.00835.x
Ito T., Tanaka H., Kimura A.
Establishment and characterization of a novel imatinib-sensitive chronic myeloid leukemia cell line MYL, and an imatinib-resistant subline MYL-R showing overexpression of Lyn.
Eur. J. Haematol. 78:417-431(2007)

Cross-references
Encyclopedic resources Wikidata; Q54907177
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number13