Cellosaurus logo
expasy logo

Cellosaurus A99 (CVCL_D699)

[Text version]
Cell line name A99
Synonyms a 99
Accession CVCL_D699
Resource Identification Initiative To cite this cell line use: A99 (RRID:CVCL_D699)
Comments Characteristics: Established from a nude mice xenograft. Tumorigenic (PubMed=21768923).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Leu (c.34_35GG>CT) (c.34_35delinsCT); Zygosity=Homozygous (PubMed=21768923).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser127Thr (c.379T>A); ClinVar=VCV000824232; Zygosity=Homozygous (PubMed=21768923).
Disease Pancreatic small cell carcinoma (NCIt: C95583)
Neuroendocrine tumor of pancreas (ORDO: Orphanet_97253)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=21768923; DOI=10.1097/MPA.0b013e3182207a58
Yachida S., Zhong Y., Patrascu R., Davis M.B., Morsberger L.A., Griffin C.A., Hruban R.H., Laheru D., Iacobuzio-Donahue C.A.
Establishment and characterization of a new cell line, A99, from a primary small cell carcinoma of the pancreas.
Pancreas 40:905-910(2011)

DOI=10.4172/2324-9293.1000104
Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D.
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

PubMed=29765522; DOI=10.18632/oncotarget.24930
Ohmoto A., Suzuki M., Takai E., Rokutan H., Fujiwara Y., Morizane C., Yanagihara K., Shibata T., Yachida S.
Establishment of preclinical chemotherapy models for gastroenteropancreatic neuroendocrine carcinoma.
Oncotarget 9:21086-21099(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D699
Encyclopedic resources Wikidata; Q54607556
Polymorphism and mutation databases Cosmic; 1767220
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number16