Cellosaurus COS/Fucci (CVCL_E071)
Cell line name | COS/Fucci |
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Synonyms | COS-Fucci |
Accession | CVCL_E071 |
Resource Identification Initiative | To cite this cell line use: COS/Fucci (RRID:CVCL_E071) |
Comments | Group: Non-human primate cell line. Characteristics: Used for study of cell cycle progression thanks to the inclusion of a Fucci (Fluorescent Ubiquitination-based Cell Cycle Indicator) construct. Characteristics: Transfected with the Fucci probe which consist of the fusion of monomeric Kusabira-Orange 2 (mKO2) to the ubiquitination domain of human CDT1 (AA 30-120) and monomeric Azami-Green (mAG) to the ubiquitination domain of human geminin (AA 1-110). Transfected with: HGNC; 24576; CDT1 (with p.Met1_Thr29del and p.Ser121_Leu546del). Transfected with: HGNC; 17493; GMNN (with p.Tyr111_Ile209del). Transfected with: UniProtKB; Q60I24; Galaxea fascicularis monomeric Azami-Green. Transfected with: UniProtKB; Q6I7B2; Fungia concinna monomeric Kusabira-Orange (with p.Lys49Glu, p.Pro70Val, p.Phe176Met, p.Lys185Glu, P.Lys188Glu, p.Ser192Asp, p.Ser196Gly and p.Leu210Gln = mKO2). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pSV6-1]. Derived from site: In situ; Kidney; UBERON=UBERON_0002113. |
Species of origin | Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534) |
Hierarchy | Parent: CVCL_0224 (COS-7) |
Sex of cell | Male |
Age at sampling | Adult |
Category | Transformed cell line |
Publications | PubMed=18267078; DOI=10.1016/j.cell.2007.12.033 |
Cross-references | |
Cell line collections (Providers) | RCB; RCB2814 |
Cell line databases/resources | CLO; CLO_0050516 |
Encyclopedic resources | Wikidata; Q54814317 |
Entry history | |
Entry creation | 22-Oct-2012 |
Last entry update | 05-Oct-2023 |
Version number | 14 |