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Cellosaurus UCSD229i-SAD1-1 (CVCL_EJ90)

[Text version]
Cell line name UCSD229i-SAD1-1
Synonyms sAD1.1; SAD1.1; UCSD-ADRC#8149-1
Accession CVCL_EJ90
Resource Identification Initiative To cite this cell line use: UCSD229i-SAD1-1 (RRID:CVCL_EJ90)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_EJ91 ! UCSD230i-SAD1-2
CVCL_EJ92 ! UCSD231i-SAD1-3
Sex of cell Female
Age at sampling 83Y
Category Induced pluripotent stem cell
Publications

PubMed=22278060; DOI=10.1038/nature10821
Israel M.A., Yuan S.H., Bardy C., Reyna S.M., Mu Y.-L., Herrera C.M., Hefferan M.P., Van Gorp S.F.J., Nazor K.L., Boscolo F.S., Carson C.T., Laurent L.C., Marsala M., Gage F.H., Remes A.M., Koo E.H., Goldstein L.S.B.
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.
Nature 482:216-220(2012)

PubMed=30686764; DOI=10.1016/j.stem.2018.12.013
van der Kant R., Langness V.F., Herrera C.M., Williams D.A., Fong L.K., Leestemaker Y., Steenvoorden E., Rynearson K.D., Brouwers J.F., Helms J.B., Ovaa H., Giera M., Wagner S.L., Bang A.G., Goldstein L.S.B.
Cholesterol metabolism is a druggable axis that independently regulates Tau and amyloid-beta in iPSC-derived Alzheimer's disease neurons.
Cell Stem Cell 24:363-375.e9(2019)

Cross-references
Cell line collections (Providers) WiCell; ucsd229i-sad1-1
Cell line databases/resources SKIP; SKIP005435
Encyclopedic resources Wikidata; Q54990035
Entry history
Entry creation26-Sep-2016
Last entry update29-Jun-2023
Version number12