| Cell line name |
BE-NQ7 |
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| Synonyms |
BE-NQ |
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| Accession |
CVCL_H585 |
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| Resource Identification Initiative |
To cite this cell line use: BE-NQ7 (RRID:CVCL_H585) |
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| Comments |
Transfected with: HGNC; 2874; NQO1. |
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| Sequence variations |
- Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Unspecified (from parent cell line).
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| Disease |
Colon carcinoma (NCIt: C4910) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_H580 (BE [Human colon carcinoma]) |
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| Sex of cell |
Male |
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| Age at sampling |
63Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=9865924
Winski S.L., Hargreaves R.H.J., Butler J., Ross D.
A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
Clin. Cancer Res. 4:3083-3088(1998) PubMed=11377380; DOI=10.1016/S0006-2952(01)00631-1
Winski S.L., Swann E., Hargreaves R.H.J., Dehn D.L., Butler J., Moody C.J., Ross D.
Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones.
Biochem. Pharmacol. 61:1509-1516(2001) |
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| Cross-references |
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| Chemistry resources |
ChEMBL-Cells; CHEMBL3307688
ChEMBL-Targets; CHEMBL614702
PubChem_Cell_line; CVCL_H585
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| Encyclopedic resources |
Wikidata; Q54795861
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| Entry history |
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| Entry creation | 11-Feb-2013 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 11 |
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