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Cellosaurus Meso37 (CVCL_H677)

[Text version]
Cell line name Meso37
Synonyms MESO37; Meso 37
Accession CVCL_H677
Resource Identification Initiative To cite this cell line use: Meso37 (RRID:CVCL_H677)
Comments Omics: SNP array analysis.
Sequence variations
  • Mutation; HGNC; 950; BAP1; Simple; p.Glu54Ter (c.160G>T); Zygosity=Heterozygous (PubMed=21642991).
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Heterozygous (PubMed=21642991).
Disease Pleural malignant mesothelioma (NCIt: C7376)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=21642991; DOI=10.1038/ng.855
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

PubMed=21774103; DOI=10.1097/JTO.0b013e318215a07d
Brevet M., Shimizu S., Bott M.J., Shukla N., Zhou Q., Olshen A.B., Rusch V.W., Ladanyi M.
Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
J. Thorac. Oncol. 6:864-874(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_H677
Biological sample resources BioSamples; SAMEA100816
Encyclopedic resources Wikidata; Q54905308
Gene expression databases GEO; GSM726276
Polymorphism and mutation databases Cosmic; 1522761
Cosmic; 1541204
Progenetix; CVCL_H677
Entry history
Entry creation11-Feb-2013
Last entry update05-Oct-2023
Version number15