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Cellosaurus CF/T43 (CVCL_HA79)

[Text version]
Cell line name CF/T43
Synonyms CF-T43; CFT43
Accession CVCL_HA79
Resource Identification Initiative To cite this cell line use: CF/T43 (RRID:CVCL_HA79)
Comments Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pZIPneoSV(X)1/SV40T].
Derived from site: In situ; Nose, nasal cavity, epithelium; UBERON=UBERON_0005384.
Cell type: Epithelial cell; CL=CL_0000066.
Sequence variations
  • Mutation; HGNC; 1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Homozygous (PubMed=15463957).
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=2472008; DOI=10.1126/science.2472008
Jetten A.M., Yankaskas J.R., Stutts M.J., Willumsen N.J., Boucher R.C.
Persistence of abnormal chloride conductance regulation in transformed cystic fibrosis epithelia.
Science 244:1472-1475(1989)

PubMed=8755664; DOI=10.1172/JCI118819
Kelley T.J., Al-Nakkash L., Cotton C.U., Drumm M.L.
Activation of endogenous deltaF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition.
J. Clin. Invest. 98:513-520(1996)

PubMed=9277448; DOI=10.1152/ajplung.1997.273.2.L363
Harris R.A., Pon D.J., Katz S., Hanrahan J.W.
Intracellular calcium responses in CF/T43 cells: calcium pools and influx pathways.
Am. J. Physiol. 273:L363-L373(1997)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Encyclopedic resources Wikidata; Q54811356
Entry history
Entry creation01-Dec-2016
Last entry update05-Oct-2023
Version number12