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Cellosaurus HEK-3KO (CVCL_HB82)

[Text version]
Cell line name HEK-3KO
Synonyms IP3R Null HEK-293
Accession CVCL_HB82
Resource Identification Initiative To cite this cell line use: HEK-3KO (RRID:CVCL_HB82)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; 6180; ITPR1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 6181; ITPR2.
Knockout cell: Method=CRISPR/Cas9; HGNC; 6182; ITPR3.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=27048566; DOI=10.1126/scisignal.aad6281
Alzayady K.J., Wang L.-W., Chandrasekhar R., Wagner L.E. II, Van Petegem F., Yule D.I.
Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca2+ release.
Sci. Signal. 9:Ra35.1-Ra35.13(2016)

Cross-references
Cell line collections (Providers) Kerafast; EUR030
Encyclopedic resources Wikidata; Q54882298
Entry history
Entry creation01-Dec-2016
Last entry update29-Jun-2023
Version number8