Cellosaurus cell line VUMC-DIPG-B (CVCL_IT44)

• Mutation; HGNC; 4776; H3C2; Simple; p.Lys28Met (c.83A>T) (H3.1K27M); Zygosity=Unspecified (PubMed=25939062).
  

PubMed=23637844; DOI=10.1371/journal.pone.0061512
Veringa S.J.E., Biesmans D., van Vuurden D.G., Jansen M.H.A., Wedekind L.E., Horsman I., Wesseling P., Vandertop W.P., Noske D.P., Kaspers G.J.L., Hulleman E.
In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma.
PLoS ONE 8:E61512-E61512(2013)

PubMed=25939062; DOI=10.1038/nm.3855
Grasso C.S., Tang Y.-J., Truffaux N., Berlow N.E., Liu L.-N., Debily M.-A., Quist M.J., Davis L.E., Huang E.C., Woo P.J., Ponnuswami A., Chen S., Johung T.B., Sun W.-C., Kogiso M., Du Y.-C., Qi L., Huang Y.-L., Hutt-Cabezas M., Warren K.E., Le Dret L., Meltzer P.S., Mao H., Quezado M., van Vuurden D.G., Abraham J., Fouladi M., Svalina M.N., Wang N., Hawkins C., Nazarian J., Alonso M.M., Raabe E.H., Hulleman E., Spellman P.T., Li X.-N., Keller C., Pal R., Grill J., Monje M.
Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.
Nat. Med. 21:555-559(2015)