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Cellosaurus Hep-2020 (CVCL_JG90)

Cell line name Hep-2020
Synonyms Hep2020
Accession CVCL_JG90
Resource Identification Initiative To cite this cell line use: Hep-2020 (RRID:CVCL_JG90)
Comments Transfected with: HGNC; 1582; CCND1.
Transfected with: HGNC; 1773; CDK4 (with p.Arg24Cys).
Transfected with: HGNC; 11730; TERT.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Disease Congenital hepatic fibrosis (NCIt: C97071)
Isolated congenital hepatic fibrosis (ORDO: Orphanet_485426)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Telomerase immortalized cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX,Y
CSF1PO12
D5S81813
D7S82012
D13S31711
D16S5399,11
TH019
TPOX8
vWA14,17

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Publications

PubMed=33060611; DOI=10.1038/s41598-020-73992-3
Nishiwaki M., Toyoda M., Oishi Y., Ishida S., Horiuchi S.-i., Makino-Itou H., Kimura T., Ohno S.-i., Ohkura T., Enosawa S., Akutsu H., Nakazawa A., Kasahara M., Kiyono T., Umezawa A.
Immortalization of human hepatocytes from biliary atresia with CDK4(R24C), cyclin D1, and TERT for cytochrome P450 induction testing.
Sci. Rep. 10:17503-17503(2020)

Cross-references
Cell line collections (Providers) JCRB; JCRB1699
Encyclopedic resources Wikidata; Q54882759
Entry history
Entry creation15-May-2017
Last entry update29-Jun-2023
Version number10