Cellosaurus cell line JMN (CVCL_M005)

• Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=21642991).
  
• Mutation; HGNC; 11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Homozygous (PubMed=1568228).
  

PubMed=7106748; DOI=10.1016/S0046-8177(82)80083-X
Behbehani A.M., Hunter W.J., Chapman A.L., Lin F.
Studies of a human mesothelioma.
Hum. Pathol. 13:862-866(1982)

PubMed=3334988
Popescu N.C., Chahinian A.P., DiPaolo J.A.
Nonrandom chromosome alterations in human malignant mesothelioma.
Cancer Res. 48:142-147(1988)

PubMed=1568228
Metcalf R.A., Welsh J.A., Bennett W.P., Seddon M.B., Lehman T.A., Pelin-Enlund K., Linnainmaa K., Tammilehto L., Mattson K., Gerwin B.I., Harris C.C.
p53 and Kirsten-ras mutations in human mesothelioma cell lines.
Cancer Res. 52:2610-2615(1992)

PubMed=21642991; DOI=10.1038/ng.855
Bott M.J., Brevet M., Taylor B.S., Shimizu S., Ito T., Wang L., Creaney J., Lake R.A., Zakowski M.F., Reva B., Sander C., Delsite R., Powell S.N., Zhou Q., Shen R.-L., Olshen A.B., Rusch V.W., Ladanyi M.
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)