Publications | PubMed=19449367; DOI=10.1002/path.2564 Snyder E.L., Sandstrom D.J., Law K., Fiore C., Sicinska E.T., Brito J., Bailey D., Fletcher J.A., Loda M., Rodig S.J., Dal Cin P.S., Fletcher C.D.M. c-Jun amplification and overexpression are oncogenic in liposarcoma but not always sufficient to inhibit the adipocytic differentiation programme. J. Pathol. 218:292-300(2009) PubMed=19706776; DOI=10.1158/0008-5472.CAN-08-4004 Muhlenberg T., Zhang Y.-X., Wagner A.J., Grabellus F., Bradner J., Taeger G., Lang H., Taguchi T., Schuler M., Fletcher J.A., Bauer S. Inhibitors of deacetylases suppress oncogenic KIT signaling, acetylate HSP90, and induce apoptosis in gastrointestinal stromal tumors. Cancer Res. 69:6941-6950(2009) PubMed=20713527; DOI=10.1158/0008-5472.CAN-10-0745 Brill E.R., Gobble R.M., Angeles C.V., Lagos-Quintana M., Crago A., Laxa B.U., DeCarolis P.L., Zhang L., Antonescu C.R., Socci N.D., Taylor B.S., Sander C., Koff A., Singer S. ZIC1 overexpression is oncogenic in liposarcoma. Cancer Res. 70:6891-6901(2010) PubMed=21335544; DOI=10.1158/0008-5472.CAN-10-3588 Gobble R.M., Qin L.-X., Brill E.R., Angeles C.V., Ugras S., O'Connor R.B., Moraco N.H., DeCarolis P.L., Antonescu C.R., Singer S. Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis. Cancer Res. 71:2697-2705(2011) PubMed=21693658; DOI=10.1158/0008-5472.CAN-11-0890 Ugras S., Brill E.R., Jacobsen A., Hafner M., Socci N.D., DeCarolis P.L., Khanin R., O'Connor R.B., Mihailovic A., Taylor B.S., Sheridan R., Gimble J.M., Viale A.J., Crago A., Antonescu C.R., Sander C., Tuschl T., Singer S. Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma. Cancer Res. 71:5659-5669(2011) PubMed=22328974; DOI=10.1158/2159-8290.CD-11-0181 Taylor B.S., DeCarolis P.L., Angeles C.V., Brenet F., Schultz N., Antonescu C.R., Scandura J.M., Sander C., Viale A.J., Socci N.D., Singer S. Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas. Cancer Discov. 1:587-597(2011) PubMed=22170698; DOI=10.1002/gcc.21917 Wu Y.V., Okada T., DeCarolis P.L., Socci N.D., O'Connor R.B., Geha R.C., Somberg C.J., Antonescu C.R., Singer S. Restoration of C/EBPalpha in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis. Genes Chromosomes Cancer 51:313-327(2012) PubMed=22911243; DOI=10.1155/2012/148614 Stratford E.W., Castro R., Daffinrud J., Skarn M., Lauvrak S., Munthe E., Myklebost O. Characterization of liposarcoma cell lines for preclinical and biological studies. Sarcoma 2012:148614.1-148614.9(2012) PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074 Teicher B.A., Polley E.C., Kunkel M., Evans D., Silvers T.E., Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J., Harris E., Monks A., Morris J. Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression. Mol. Cancer Ther. 14:2452-2462(2015) PubMed=26643872; DOI=10.18632/oncotarget.6464 Kanojia D., Nagata Y., Garg M., Lee D.H., Sato A., Yoshida K., Sato Y., Sanada M., Mayakonda A., Bartenhagen C., Klein H.-U., Doan N.B., Said J.W., Mohith S., Gunasekar S., Shiraishi Y., Chiba K., Tanaka H., Miyano S., Myklebost O., Yang H., Dugas M., Meza-Zepeda L.A., Silberman A.W., Forscher C., Tyner J.W., Ogawa S., Koeffler H.P. Genomic landscape of liposarcoma. Oncotarget 6:42429-42444(2015) |