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Cellosaurus HD-MB03 (CVCL_S506)

[Text version]
Cell line name HD-MB03
Accession CVCL_S506
Resource Identification Initiative To cite this cell line use: HD-MB03 (RRID:CVCL_S506)
Comments Doubling time: 23.32 hours (Note=Early passage), 23.98 hours (Note=Late passage) (PubMed=23054560); ~48 hours (DSMZ=ACC-740).
Omics: Array-based CGH.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=23054560).
Disease Medulloblastoma, non-WNT/non-SHH, group 3 (NCIt: C129445)
Medulloblastoma (ORDO: Orphanet_616)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133824,27
D3S135814,15
D5S81811
D7S8209,10
D8S117912,14
D13S31711,12
D16S5399,11
D18S5112,13
D19S43314,15
D21S1130,31.2
FGA21,22
Penta D9,14
Penta E5,15
TH016,9.3
TPOX8,11
vWA18,19

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Publications

PubMed=23054560; DOI=10.1007/s11060-012-0978-1
Milde T., Lodrini M., Savelyeva L., Korshunov A., Kool M., Brueckner L.M., Antunes A.S.L.M., Oehme I., Pekrun A., Pfister S.M., Kulozik A.E., Witt O., Deubzer H.E.
HD-MB03 is a novel group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.
J. Neurooncol. 110:335-348(2012)

PubMed=27498314; DOI=10.1016/j.jbiotec.2016.07.028
Ivanov D.P., Coyle B., Walker D.A., Grabowska A.M.
In vitro models of medulloblastoma: choosing the right tool for the job.
J. Biotechnol. 236:10-25(2016)

PubMed=27812533; DOI=10.1016/j.dib.2016.10.004
Ivanov D.P., Walker D.A., Coyle B., Grabowska A.M.
Data on the number and frequency of scientific literature citations for established medulloblastoma cell lines.
Data Brief 9:696-698(2016)

Cross-references
Cell line collections (Providers) DSMZ; ACC-740
Cell line databases/resources DSMZCellDive; ACC-740
Encyclopedic resources Wikidata; Q54882097
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number15