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Cellosaurus RMS559 (CVCL_S640)

[Text version]
Cell line name RMS559
Synonyms RMS559/R31
Accession CVCL_S640
Resource Identification Initiative To cite this cell line use: RMS559 (RRID:CVCL_S640)
Sequence variations
  • Mutation; HGNC; 3691; FGFR4; Simple; p.Val550Leu (c.1648G>C); Zygosity=Unspecified (PubMed=22142829).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=12370270; DOI=10.1172/JCI15634
Panigrahy D., Singer S., Shen L.Q., Butterfield C.E., Freedman D.A., Chen E.J., Moses M.A., Kilroy S., Duensing S., Fletcher C.D.M., Fletcher J.A., Hlatky L., Hahnfeldt P., Folkman J., Kaipainen A.
PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis.
J. Clin. Invest. 110:923-932(2002)

PubMed=22142829; DOI=10.1158/1078-0432.CCR-11-2056
Shukla N., Ameur N., Yilmaz I., Nafa K., Lau C.-Y., Marchetti A., Borsu L., Barr F.G., Ladanyi M.
Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways.
Clin. Cancer Res. 18:748-757(2012)

PubMed=23882450; DOI=10.3389/fonc.2013.00183
Hinson A.R.P., Jones R., Crose L.E.S., Belyea B.C., Barr F.G., Linardic C.M.
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Front. Oncol. 3:183.1-183.12(2013)

PubMed=23665679; DOI=10.1038/onc.2013.129
Sokolowski E., Turina C.B., Kikuchi K., Langenau D.M., Keller C.
Proof-of-concept rare cancers in drug development: the case for rhabdomyosarcoma.
Oncogene 33:1877-1889(2014)

Cross-references
Encyclopedic resources Wikidata; Q54950715
Polymorphism and mutation databases Cosmic; 1718097
Cosmic; 2355958
Entry history
Entry creation03-Feb-2014
Last entry update21-Mar-2023
Version number11