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Cellosaurus MaWi (CVCL_S810)

Cell line name MaWi
Synonyms Mawi; MAWI; MAwi
Accession CVCL_S810
Resource Identification Initiative To cite this cell line use: MaWi (RRID:CVCL_S810)
Comments Characteristics: Established from a nude mice xenograft.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=12068308).
Disease Colorectal adenocarcinoma (NCIt: C5105)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=6686962; DOI=10.1016/s0232-1513(83)80010-3
Lewis J.C., Smith P.A., Keep P.A., Boxer G.M.
A comparison of the content and immunohistochemical patterns of CEA-like activity in human colorectal tumours and nude mouse xenografts.
Exp. Pathol. 24:227-235(1983)

PubMed=8512814; DOI=10.1038/bjc.1993.241
Baer J.C., Freeman A.A., Newlands E.S., Watson A.J., Rafferty J.A., Margison G.P.
Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.
Br. J. Cancer 67:1299-1302(1993)

PubMed=12068308; DOI=10.1038/nature00766
Davies H., Bignell G.R., Cox C., Stephens P.J., Edkins S., Clegg S., Teague J.W., Woffendin H., Garnett M.J., Bottomley W., Davis N., Dicks E., Ewing R., Floyd Y., Gray K., Hall S., Hawes R., Hughes J., Kosmidou V., Menzies A., Mould C., Parker A., Stevens C., Watt S., Hooper S., Wilson R., Jayatilake H., Gusterson B.A., Cooper C.S., Shipley J.M., Hargrave D., Pritchard-Jones K., Maitland N.J., Chenevix-Trench G., Riggins G.J., Bigner D.D., Palmieri G., Cossu A., Flanagan A.M., Nicholson A., Ho J.W.C., Leung S.Y., Yuen S.T., Weber B.L., Seigler H.F., Darrow T.L., Paterson H.F., Marais R., Marshall C.J., Wooster R., Stratton M.R., Futreal P.A.
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S810
Encyclopedic resources Wikidata; Q54904068
Polymorphism and mutation databases Cosmic; 687534
Entry history
Entry creation03-Feb-2014
Last entry update05-Oct-2023
Version number10