Cellosaurus cell line 2645-94 (CVCL_S816)

• Gene fusion; HGNC; 2726; DDIT3 + HGNC; 4010; FUS; Name(s)=FUS-DDIT3, TLS-CHOP (PubMed=16651630).
  

PubMed=10449603; DOI=10.1002/(SICI)1097-0215(19990924)83:1<30::AID-IJC6>3.0.CO;2-4
Thelin-Jarnum S., Lassen C., Panagopoulos I., Mandahl N., Aman P.
Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas.
Int. J. Cancer 83:30-33(1999)

PubMed=16651630; DOI=10.2353/ajpath.2006.050872
Engstrom K., Willen H., Kabjorn-Gustafsson C., Andersson C., Olsson M., Goransson M., Thelin-Jarnum S., Olofsson A., Warnhammar E., Aman P.
The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells.
Am. J. Pathol. 168:1642-1653(2006)

PubMed=20515481; DOI=10.1186/1471-2407-10-249
Andersson M.K., Goransson M., Olofsson A., Andersson C., Aman P.
Nuclear expression of FLT1 and its ligand PGF in FUS-DDIT3 carrying myxoid liposarcomas suggests the existence of an intracrine signaling loop.
BMC Cancer 10:249.1-249.10(2010)

PubMed=25393000; DOI=10.1371/journal.pone.0113110
Stahlberg A., Kabjorn-Gustafsson C., Engtrom K., Thomsen C., Dolatabadi S., Jonasson E., Li C.-Y., Ruff D., Chen S.-M., Aman P.
Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.
PLoS ONE 9:E113110-E113110(2014)

PubMed=30962207; DOI=10.15252/embr.201845766
Linden M., Thomsen C., Grundevik P., Jonasson E., Andersson D., Runnberg R., Dolatabadi S., Vannas C., Santamaria M.L., Fagman H., Stahlberg A., Aman P.
FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.
EMBO Rep. 20:e45766.1-e45766.15(2019)