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Cellosaurus AY-27 (CVCL_S825)

[Text version]
Cell line name AY-27
Synonyms AY 27; AY27
Accession CVCL_S825
Resource Identification Initiative To cite this cell line use: AY-27 (RRID:CVCL_S825)
Comments Characteristics: Tumorigenic.
Doubling time: 0.927 +- 0.206 days (PubMed=2936252).
Transformant: ChEBI; CHEBI:82328; Nifurthiazole (N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide; FANFT).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Transitional cell carcinoma of the rat urinary bladder (NCIt: C64161)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344.
Sex of cell Male
Category Cancer cell line
Publications

PubMed=7298281
Cohen S.M., Yang J.P.S., Jacobs J.B., Arai M., Fukushima S., Friedell G.H.
Transplantation and cell culture of rat urinary bladder carcinoma.
Invest. Urol. 19:136-141(1981)

PubMed=2981157
Chlapowski F.J., Nemecek G.M.
Aberrant cyclic adenosine 3':5'-monophosphate metabolism in cultures of tumorigenic rat urothelium.
Cancer Res. 45:122-127(1985)

PubMed=2936252
Shulok J.R., Klaunig J.E., Selman S.H., Schafer P.J., Goldblatt P.J.
Cellular effects of hematoporphyrin derivative photodynamic therapy on normal and neoplastic rat bladder cells.
Am. J. Pathol. 122:277-283(1986)

PubMed=10574249; DOI=10.1038/sj.bjc.6690741
Xiao Z., McCallum T.J., Brown K.M., Miller G.G., Halls S.B., Parney I., Moore R.B.
Characterization of a novel transplantable orthotopic rat bladder transitional cell tumour model.
Br. J. Cancer 81:638-646(1999)

PubMed=20404568; DOI=10.4161/cbt.9.12.11638
Vandepitte J., Maes J., Van Cleynenbreugel B., Van Poppel H., Lerut E., Agostinis P., de Witte P.A.M.
An improved orthotopic rat bladder tumor model using Dil-loaded fluorescent AY-27 cells.
Cancer Biol. Ther. 9:986-993(2010)

PubMed=21424013; DOI=10.1039/c0pp00393j
Ekroll I.K., Gederaas O.A., Helander L., Hjelde A., Melo T.B., Johnsson A.
Photo induced hexylaminolevulinate destruction of rat bladder cells AY-27.
Photochem. Photobiol. Sci. 10:1072-1079(2011)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) Millipore; SCC254
Chemistry resources ChEMBL-Cells; CHEMBL4482253
PubChem_Cell_line; CVCL_S825
Encyclopedic resources Wikidata; Q54752001
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number11