| Cell line name |
CHO 25-RA |
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| Synonyms |
25-RA; 25RA; Clone 25-RA; 25 RA CHO |
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| Accession |
CVCL_U429 |
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| Resource Identification Initiative |
To cite this cell line use: CHO 25-RA (RRID:CVCL_U429) |
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| Comments |
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064. |
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| Sequence variations |
- Mutation; UniProtKB; P97260; Scap; Simple; p.Asp443Asn (c.1327G>A); Zygosity=Heterozygous (PubMed=8898195).
|
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| Species of origin |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
(NCBI Taxonomy: 10029) |
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| Hierarchy |
Parent: CVCL_0214 (CHO-K1)
Children:
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| Sex of cell |
Female |
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| Age at sampling |
Adult |
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| Category |
Spontaneously immortalized cell line |
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| Publications | PubMed=6105157; DOI=10.1016/S0021-9258(19)43901-X
Chang T.-Y., Limanek J.S.
Regulation of cytosolic acetoacetyl coenzyme A thiolase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A reductase, and mevalonate kinase by low density lipoprotein and by 25-hydroxycholesterol in Chinese hamster ovary cells.
J. Biol. Chem. 255:7787-7795(1980) PubMed=3335499; DOI=10.1016/S0021-9258(19)57389-6
Cadigan K.M., Heider J.G., Chang T.-Y.
Isolation and characterization of Chinese hamster ovary cell mutants deficient in acyl-coenzyme A:cholesterol acyltransferase activity.
J. Biol. Chem. 263:274-282(1988) PubMed=2404988; DOI=10.1083/jcb.110.2.295
Cadigan K.M., Spillane D.M., Chang T.-Y.
Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking.
J. Cell Biol. 110:295-308(1990) PubMed=8898195; DOI=10.1016/S0092-8674(00)81362-8
Hua X.-X., Nohturfft A., Goldstein J.L., Brown M.S.
Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein.
Cell 87:415-426(1996) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54812550
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| Entry history |
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| Entry creation | 03-Feb-2014 |
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| Last entry update | 30-Jan-2024 |
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| Version number | 10 |
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