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Cellosaurus OC/CDE 22 (CVCL_U976)

[Text version]
Cell line name OC/CDE 22
Synonyms OC/CDE-22; OC/CDE22; Oval Cell/Choline Deficient Ethionine-supplemented 22 weeks diet
Accession CVCL_U976
Resource Identification Initiative To cite this cell line use: OC/CDE 22 (RRID:CVCL_U976)
Comments Doubling time: 45 hours (PubMed=7679995).
Transformant: ChEBI; CHEBI:68664; DL-ethionine.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Cell type: Hepatic oval stem cell; CL=CL_0002196.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley.
Hierarchy Children:
CVCL_U978 (M22)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=7679995; DOI=10.1006/excr.1993.1025
Pack R., Heck R., Dienes H.-P., Oesch F., Steinberg P.
Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells from carcinogen-fed rats.
Exp. Cell Res. 204:198-209(1993)

PubMed=7526039
Steinberg P., Steinbrecher R., Radaeva S., Schirmacher P., Dienes H.-P., Oesch F., Bannasch P.
Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation.
Lab. Invest. 71:700-709(1994)

PubMed=7532542
Radaeva S., Steinberg P.
Phenotype and differentiation patterns of the oval cell lines OC/CDE 6 and OC/CDE 22 derived from the livers of carcinogen-treated rats.
Cancer Res. 55:1028-1038(1995)

PubMed=11751433; DOI=10.1093/carcin/22.12.2009
Komlosh A., Volohonsky G., Porat N., Tuby C., Bluvshtein E., Steinberg P., Oesch F., Stark A.A.
Gamma-glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines.
Carcinogenesis 22:2009-2016(2001)

PubMed=12075625; DOI=10.1093/carcin/23.4.669
Komlosh A., Volohonsky G., Porat N., Tuby C., Bluvshtein E., Steinberg P., Oesch F., Stark A.A.
Correction: Gamma-glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines.
Carcinogenesis 23:671-678(2002)

Cross-references
Anatomy/cell type resources BTO; BTO:0002198
Encyclopedic resources Wikidata; Q54931716
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number10