Snapshot Issue 19 February 2006


Were it not for the coiled coil…

Cupidin …
A protein neither short nor long
Whose arrow flirts with the brain
And knows how to touch the heart
Whose coiled coil has seduced many
From glutamate receptors to the actin cytoskeleton.

A protein which embraces
And coaxes its partners to the post-synaptic density
From where they are eased into the neuron’s membrane
To blossom
To communicate
To guide.

From Drosophila to Man
Whose lace and unlace
Goads its allies into a waltz
Bestows suppleness on synapses
Escorts axons along their path
…and lends its share of pain.

Another poem in: Shiraishi Y., Mizutani A., Yuasa S., Mikoshiba K., Furuichi T., "Glutamate-induced declustering of post-synaptic adaptor protein Cupidin (Homer 2/vesl-2) in cultured cerebellar granule cells", J. Neurochem. 87:364-376(2003) PMID: 14511114

Cupidin (Homer protein homolog 2), Homa sapiens (human): Q9NSB8

L'édition française de cette chronique est disponible dans l'Instantanés du mois de Prolune.

Need to reference this article ? Please use this link:


Post a comment


Please refrain from off-topic banter and personal attacks. Your comment may be edited or removed at the discretion of Protein Spotlight editors. Our goal is not to stifle debate but to keep it relevant.

No HTML tags allowed. If you wish to specify a link to another site, write it in full without any kind of formating and it shall appear live automagically.


Interested in writing for Protein Spotlight? Do you have an idea for an article? Describe it in two or three sentences and use our Contact page to send it to us.

Visitors since September 14th, 2010:

vBulletin stats