Variant position: 303 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 354 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GYQVTMKTAKVAASDWTFLH CLPRKPEEVDDEVFYSPRSLV
Mouse GYQVTMKTAKVAASDWTFLH CLPRKPEEVDDEVFYSPRSLV
Rat GYQVTMKTAKVAASDWTFLH CLPRKPEEVDDEVFYSPRSLV
Bovine GYQVTMKTAKVAAPDWTFLH CLPRKPEEVDDEVFYSPRSLV
Sheep GYQVNSKTAKVAASAWTFLH CLPRKPEEVDDDVFYSPRSLV
Chicken GYQITMQTVQSAASNWTFLH CLPRKPEEVDDEVFYSPRSLV
Baker's yeast GFQINQELVSVADPNYKFMH CLPRHQEEVSDDVFYGEHSIV
Fission yeast GFQVTGEIMKLAKPSCKFMH CLPRHPEEVSDEVFYGENSLV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
33 – 354 Ornithine carbamoyltransferase, mitochondrial
302 – 305 Ornithine binding
303 – 303
289 – 289 N6-succinyllysine
292 – 292 N6-acetyllysine; alternate
292 – 292 N6-succinyllysine; alternate
307 – 307 N6-acetyllysine; alternate
307 – 307 N6-succinyllysine; alternate
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.