Variant position: 183 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 427 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human M--NRGSTPYGGVKLEDLIVKD GLTDVYNKIHMGSCAENTAKK
Mouse M--SRGATPYGGVKLEDLIVKD GLTDVYNKIHMGNCAENTA
Rat M--SRGATPYGGVKLEDLIVKD GLTDVYNKIHMGNCAENTA
Bovine M--NRGATPYGGVKLEDLIVKD GLTDVYNKIHMGNCAENTA
Xenopus tropicalis M--SRGATPYGGVKLEDIIVKD GLTDVYNKFHMGNCAENTA
Zebrafish M--AREAPPYGGVKMEDLIVKD GLTDVYNKFHMGNCAENTA
Baker's yeast MPAARAGAKFGQTVLVDGVERD GLNDAYDGLAMGVHAEKCA
Fission yeast APKNRFGAKYGNVELVDGLLRD GLSDAYDGLPMGNAAELCA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
34 – 427 Acetyl-CoA acetyltransferase, mitochondrial
174 – 174 N6-acetyllysine; alternate
174 – 174 N6-succinyllysine; alternate
181 – 181 N6-acetyllysine; alternate
181 – 181 N6-succinyllysine; alternate
190 – 190 N6-acetyllysine; alternate
190 – 190 N6-succinyllysine; alternate
202 – 202 N6-acetyllysine; alternate
202 – 202 N6-succinyllysine; alternate
163 – 427 Missing. In isoform 2.
No reference for the current variant in UniProtKB/Swiss-Prot.
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