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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q8TDV5: Variant p.Ser309Leu

Glucose-dependent insulinotropic receptor
Gene: GPR119
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Variant information Variant position: help 309
Type of variant: help LB/B
Residue change: help From Serine (S) to Leucine (L) at position 309 (S309L, p.Ser309Leu).
Physico-chemical properties: help Change from small size and polar (S) to medium size and hydrophobic (L)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 309
Protein sequence length: help 335
Location on the sequence: help QLYHMALGVKKVLTSFLLFL S ARNCGPERPRESSCHIVTIS
Residue conservation: help 
Human                         QLYHMALGV------------------------KKVLTS-----------------FLLFLSARNCGPERPRES----------------------------------------------------------------------SCHIVTIS

Mouse                         QLYHMALGV------------------------KKFFTS--

Rat                           QLCHMALGLLADGSTQPQIETLKGKEERKKVGRKTLYTCDA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 335 Glucose-dependent insulinotropic receptor
Topological domain 284 – 335 Cytoplasmic



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.