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ABCD

ABCD_AX483 in the ABCD (AntiBodies Chemically Defined) Database

Antigen information
Target type Protein
Target link UniProt: P10600 Homo sapiens (Human)
Target name TGFB3, Transforming growth factor beta-3, TGF-beta-3
Epitope This antibody binds to the beta6/beta7 hairpin region of TGFB3
Antibody information
Antibody name h2A10.V4
Antibody synonyms MTBT1466A, Humanized 2A10, Anti-TGFB3, Anti-TGFB3-h2A10.V4
Comments Binding of this antibody to TGFB3 blocks TGFBR2 binding and inhibits the TGFBR1/TGFBR2 signaling receptors.
Applications ELISA, Surface plasmon resonance, X-ray crystallography
Cross-references PDB: 8V52
Publications Patent: WO2021188749
PMID: 34349032
PMID: 38272035
Would you like to obtain this antibody?
It can be produced at the Geneva Antibody facility (for more information, please check here).