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ABCD

ABCD_BF052 in the ABCD (AntiBodies Chemically Defined) Database

Antigen information
Target type Protein
Target link UniProt: P05877 Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1)
UniProt: Q7SQ39 Human immunodeficiency virus type 1 (HIV-1)
Target name Env, Envelope glycoprotein gp160, Env polyprotein
Epitope Surface protein gp120, SU, Glycoprotein 120, gp120
Sequence:
SVQINCTRPNY
Sequence:
KQIINMWQEVG
Antibody information
Antibody name anti-E-gp120 YZ23
Antibody synonyms YZ23, Hybridoma YZ23 derived
Comments Irreversibly binds gp120
Neutralizes CCR5-dependent subtype A–C HIV strains
Applications Neutralization, X-ray crystallography, ELISA
Cross-references PDB: 3CLE
PDB: 3CLF
Publications PMID: 19726674
PMID: 12665517
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