Home  |  Contact

Frequently asked questions (FAQ)

What is the ABCD Database?
The ABCD is a database of chemically defined antibodies, i.e. all antibodies with a known primary sequence, and with a known target (to which, most often, a UniProtKB or ChEBI ID can be attributed).

How can I search antibodies in the database?
You can search the database using the name of an antibody. However, we cannot guarantee that all possible names and synonyms used in the literature for a given antibody will be included on the database. The most reliable way is to search using information about the target, such as target name, UniProtKB or ChEBI identifiers, or species.

Which information is available for a given antibody?
For each antibody, we provide the following information:

How can I obtain the sequence of a given antibody?
A vast majority of antibodies included in the ABCD database are described in published literature. For each antigen-binding element, we provide upon request the protein sequence of the heavy and light variable chains (or, in the case of camelid antibodies, only the heavy chain). Since the Intellectual Property status of each antibody is different, this information is provided only for academic research purpose.

With the protein sequence, can I produce myself an antibody to use in my research?
Yes. However, you need to have appropriate knowledge and tools to produce an antibody with sufficient yields to be used in most common biological applications. In each antibody page at the ABCD database, we provide ordering links to our academic production facility, located in Geneva.

Can I order the same antibodies described in the database from a commercial provider?
Commercial versions of some of the antibodies included on the database can be found in the catalogs of established companies. However, as each company frequently uses a different name for the same antibody, you need to carefully check which is the right one for you.

I found missing or incorrect information in one (or several) entry(ies) in the ABCD database. How can I signal these mistakes?
If you find something wrong or amiss, please contact us (use the "Contact" link on the top right of all ABCD web pages).

I have sequenced some hybridomas, and/or I have sequences coming from phage/yeast display projects. How can I submit these sequences to the ABCD database?
If you want to contribute to our initiative by submitting new antibody sequences, check the guidelines on the Submission page .

I would like to download the full database. How can I proceed?
You can obtain the file containing the full database by sending us a message, using the Contact link on the top right menu.