Cell line name | HDLM-2 | ||||||||||||||||||
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Synonyms | HD-LM-2; HDLM2 | ||||||||||||||||||
Accession | CVCL_0009 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: HDLM-2 (RRID:CVCL_0009) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Part of: LL-100 blood cancer cell line panel. Doubling time: ~70-75 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Cell surface proteome. Omics: Deep antibody staining analysis. Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Pleural effusion. | ||||||||||||||||||
Sequence variations | TP53 p.Ser261fs c.?(782delins) (PubMed=17065008). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Hodgkin lymphoma (NCIt: C9357) Hodgkin lymphoma (ORDO: Orphanet_98293) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Children:
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Originate from same individual | CVCL_M693 ! HDLM-1 CVCL_M697 ! HDLM-3 | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | 74Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; DSMZ Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | http://www.proteinatlas.org/learn/cellines | ||||||||||||||||||
Publications | PubMed=3713248; DOI=10.1016/0145-2126(86)90084-6 PubMed=2602652; DOI=10.1007/978-3-642-83781-4_8 PubMed=2690233; DOI=10.1007/978-3-642-83781-4_5 PubMed=8558920 PubMed=9685479; DOI=10.1093/nar/26.16.3651 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=12581897; DOI=10.1016/S0165-4608(02)00656-8 PubMed=17065008; DOI=10.1080/10428190600667721 PubMed=20164919; DOI=10.1038/nature08768 PubMed=22460905; DOI=10.1038/nature11003 PubMed=25894527; DOI=10.1371/journal.pone.0121314 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=29533902; DOI=10.1515/hsz-2017-0321 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=31160637; DOI=10.1038/s41598-019-44491-x | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | DSMZ; ACC-17 | ||||||||||||||||||
Cell line databases/resources | CLDB; cl1580
CCLE; HDLM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Cell_Model_Passport; SIDM01064 Cosmic-CLP; 924110 DepMap; ACH-000267 IGRhCellID; HDLM2 LINCS_LDP; LCL-2007 | ||||||||||||||||||
Ontologies | CLO; CLO_0003671 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03473364
BioSample; SAMN10988513 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308234
ChEMBL-Targets; CHEMBL2366231 GDSC; 924110 PharmacoDB; HDLM2_521_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 ArrayExpress; E-MTAB-7721 ArrayExpress; E-MTAB-7722 GEO; GSM335390 GEO; GSM381298 GEO; GSM499724 GEO; GSM499732 GEO; GSM552430 GEO; GSM646534 GEO; GSM887064 GEO; GSM888134 GEO; GSM1669870 | ||||||||||||||||||
Other | Wikidata; Q54882175 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 924110
Cosmic; 988701 Cosmic; 1013909 Cosmic; 1086355 Cosmic; 1278832 Cosmic; 1289699 Cosmic; 1290220 Cosmic; 1432040 Cosmic; 2276322 Cosmic; 2464309 IARC_TP53; 23613 Progenetix; CVCL_0009 | ||||||||||||||||||
Proteomic databases | PRIDE; PXD000589 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 31 |