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Cellosaurus U-266/84 (CVCL_0016)

[Text version]

Cell line name U-266/84
Accession CVCL_0016
Resource Identification Initiative To cite this cell line use: U-266/84 (RRID:CVCL_0016)
Comments Characteristics: Produces IgE lambda.
Omics: Deep antibody staining analysis.
Omics: Deep RNAseq analysis.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for BRAF p.Lys601Asn (c.1803A>T) (ClinVar=VCV000376285) (from parent cell line).
Heterozygous for MSH6 p.Gly141Asp (c.422G>A) (from parent cell line).
Homozygous for TP53 p.Ala161Thr (c.481G>A) (ClinVar=VCV000161518) (from parent cell line).
Homozygous for TRAF3 p.Lys550Leufs*3 (c.1648_1649insT) (from parent cell line).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0566 (U266B1)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Web pages http://www.proteinatlas.org/learn/cellines

PubMed=3133230; DOI=10.1002/eji.1830180611
Hellman L., Josephson S., Jernberg H., Nilsson K., Pettersson U.
Immunoglobulin synthesis in the human myeloma cell line U-266 expression of two immunoglobulin heavy chain isotypes (epsilon and alpha) after long-term cultivation in vitro.
Eur. J. Immunol. 18:905-910(1988)

Other Wikidata; Q54973558
Entry history
Entry creation04-Apr-2012
Last entry update29-Oct-2020
Version number16